NFAT5

Across TCGA patient cohorts, NFAT5 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,350 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NFAT5-associated proteins across cancer lineages are EDC4, ALG14, and IST1. Each is linked with NFAT5 in more than 3 cancer types. Because this analysis shows association rather than direction, both NFAT5-to-partner and partner-to-NFAT5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NFAT5 versus EDC4 in OV, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NFAT5→partner) and Y-score (partner→NFAT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EDC4 →	+0.222	+1.161	<.001	<.001	3	3
PDAC	ALG14 →	-0.498	-0.481	.003	<.001	3	3
BRCA	IST1 →	+0.221	+0.815	<.001	<.001	3	3
LUAD	APRT →	+0.401	+0.381	<.001	<.001	3	3
PDAC	NUTF2 →	+0.507	+0.303	.004	.009	2	4
LSCC	NFAT5_S561 →	+0.452	+0.495	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,350 associations by consensus.

NFAT5 vs EDC4 — OV

Explore this scatter interactively →