NFAT5

Across TCGA patient cohorts, NFAT5 protein abundance is significantly associated with the RNA expression of many other genes, with 5,430 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NFAT5-associated genes across cancer lineages are SNTB2, TMC7, and THAP11. Each is linked with NFAT5 in more than 3 cancer types. Because this analysis shows association rather than direction, both NFAT5-to-partner and partner-to-NFAT5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NFAT5 versus SNTB2 in LSCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFAT5→partner) and Y-score (partner→NFAT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SNTB2 →	+0.424	+0.294	.001	<.001	3	4
COAD	TMC7 →	+1.206	+0.660	.003	.003	3	3
LSCC	THAP11 →	+0.495	+0.257	<.001	.001	3	3
PDAC	PIP5K1B →	-0.861	-0.190	.002	.009	3	3
LSCC	NIP7 →	+0.599	+0.321	<.001	<.001	3	3
PDAC	BLK →	-0.805	-0.197	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,430 associations by consensus.

NFAT5 vs SNTB2 — LSCC

Explore this scatter interactively →