NFAT5

Across TCGA patient cohorts, NFAT5 protein abundance is significantly associated with the protein abundance of many other proteins, with 12,192 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NFAT5-associated proteins across cancer lineages are NFAT5_S561, DDX19A, and ADGRG1. Each is linked with NFAT5 in more than 5 cancer types. Because this analysis shows association rather than direction, both NFAT5-to-partner and partner-to-NFAT5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NFAT5 versus NFAT5_S561 in LSCC, with a Pearson correlation of 0.74.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NFAT5→partner) and Y-score (partner→NFAT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NFAT5_S561 →	+0.665	+0.344	<.001	<.001	3	6
HNSC	DDX19A →	+0.280	+0.283	<.001	<.001	3	4
HNSC	ADGRG1 →	+0.570	+0.293	<.001	<.001	3	3
HNSC	CHMP1A →	+0.304	+0.350	<.001	<.001	3	3
LSCC	CLIP2 →	+0.327	+0.281	<.001	<.001	3	3
BRCA	CLIP2_S42 →	+0.797	+0.252	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,192 associations by consensus.

NFAT5 vs NFAT5_S561 — LSCC

Explore this scatter interactively →