NFAT5

Across TCGA cell cohorts, NFAT5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,969 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NFAT5-associated GO terms across cancer lineages are R-loop processing, Vacuolar transport, and Establishment of protein localization to vacuole. Each is linked with NFAT5 in more than 17 cancer types. Because this analysis shows association rather than direction, both NFAT5-to-partner and partner-to-NFAT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, R-loop processing grouped by NFAT5-low versus NFAT5-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFAT5→partner) and Y-score (partner→NFAT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	R-loop processing →	+0.118	+0.929	<.001	.001	3	18
BONE	Vacuolar transport →	+0.076	+1.218	.001	<.001	3	17
BONE	Establishment of protein localization to vacuole →	+0.103	+1.457	<.001	<.001	3	17
BREAST	Viral transcription →	+0.101	+1.059	<.001	<.001	3	16
BONE	Late viral transcription →	+0.203	+1.299	<.001	<.001	3	16
BONE	Regulation of hippo signaling →	+0.113	+1.287	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,969 associations by consensus.

R-loop processing by NFAT5 expression — LUNG_SCLC

Explore this box plot interactively →