NFASC

Across TCGA pan-cancer cohorts, NFASC Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NFASC data layer compared with 24 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NFASC Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated NFASC expression acts as an unfavorable survival marker, although some lineages such as UCEC and STAD show a favorable association.

UCEC, LUAD, and STAD are the cancer types where NFASC Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.828	0.604	<.001	36	view →
LUAD	DFS	Median	IV	0.342	0.893	<.001	14	view →
STAD	OS	Median	All	0.906	0.672	.022	12	view →
GBM	OS	Median	All	0.020	0.416	<.001	6	view →
SKCM	DFS	Median	All	0.930	0.734	.040	3	view →
COAD	OS	Median	II,III,IV	0.924	0.767	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NFASC–UCEC (DFS)

Open the UCEC breakdown →