NFAM1

Across TCGA patient cohorts, NFAM1 mutation is significantly associated with the RNA expression of many other genes, with 1,487 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NFAM1-associated genes across cancer lineages are LYZL1, BCAR1P2, and RNU6-13P. Each is linked with NFAM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NFAM1-to-partner and partner-to-NFAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LYZL1 grouped by NFAM1-low versus NFAM1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFAM1→partner) and Y-score (partner→NFAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LYZL1 →	+0.042	+5.418	<.001	.005	3	2
CESC	BCAR1P2 →	+0.070	+6.144	<.001	.001	3	2
UCEC	RNU6-13P →	+0.236	+2.269	.003	.003	3	2
UCEC	IMP3P2 →	+0.144	+2.369	.001	<.001	3	2
UCEC	RNA5SP422 →	+0.615	+1.893	.001	.008	3	2
LUAD	SNRPGP16 →	+0.223	+7.930	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,487 associations by consensus.

LYZL1 by NFAM1 expression — CESC

Explore this box plot interactively →