NF1P8

Across TCGA pan-cancer cohorts, NF1P8 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of NF1P8’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where NF1P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NF1P8 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

LUSC, HNSC, and BRCA are the cancer types where NF1P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NF1P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.453	.005	4	view →
HNSC	All	II,III,IV	+0.145	.018	4	view →
BRCA	All	All	+0.040	.009	4	view →
UCEC	All	II,III,IV	+0.483	.044	2	view →
KIRC	Male	All	−0.004	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

NF1P8–LUSC

Open the LUSC breakdown →