NF1P1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NF1P1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NF1P1-associated genes across cancer lineages are MIR412, RNU6-591P, and MIR4476. Each is linked with NF1P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NF1P1-to-partner and partner-to-NF1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR412 grouped by NF1P1-low versus NF1P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NF1P1→partner) and Y-score (partner→NF1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR412 →+0.621+8.066<.001.00731
UCECRNU6-591P →+0.652+8.066<.001.00731
UCECMIR4476 →+0.736+8.066<.001.00731
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MIR412 by NF1P1 expression — UCEC

Box plot of MIR412 in NF1P1-low vs NF1P1-high samples in UCEC.

Explore this box plot interactively →

Exploration