NEXN

Across TCGA cell cohorts, NEXN RNA expression is significantly associated with the go_rna of many other GO terms, with 5,608 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NEXN-associated GO terms across cancer lineages are Collagen fibril organization, Establishment of epithelial cell apical/basal polarity, and Peptidyl-lysine oxidation. Each is linked with NEXN in more than 13 cancer types. Because this analysis shows association rather than direction, both NEXN-to-partner and partner-to-NEXN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen fibril organization grouped by NEXN-low versus NEXN-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEXN→partner) and Y-score (partner→NEXN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Collagen fibril organization →	+0.365	+3.221	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	+0.236	+2.552	.004	.006	2	14
BONE	Peptidyl-lysine oxidation →	+1.639	+3.088	<.001	<.001	3	13
BONE	Dentinogenesis →	+1.851	+2.538	<.001	<.001	3	12
BONE	Regulation of mesenchymal stem cell proliferation →	+0.235	+2.748	<.001	<.001	3	12
BONE	Positive regulation of mesenchymal stem cell proliferation →	+0.235	+2.748	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,608 associations by consensus.

Collagen fibril organization by NEXN expression — BONE

Explore this box plot interactively →