NEUROG2-AS1

Across TCGA pan-cancer cohorts, NEUROG2-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated NEUROG2-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher NEUROG2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NEUROG2-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and UCS show a favorable association.

KIRC, MESO, and OV are the cancer types where NEUROG2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.240	0.562	<.001	93	view →
MESO	OS	Tertile	II,III,IV	0.246	0.456	<.001	83	view →
OV	OS	Tertile	II,III,IV	0.887	0.824	.025	50	view →
UVM	OS	Quartile	III,IV	0.199	1.000	.001	46	view →
ACC	DFS	Median	All	0.238	0.693	<.001	44	view →
KIRP	DFS	Tertile	III,IV	0.169	0.643	.001	36	view →
THYM	DFS	Tertile	III,IV	0.317	0.913	<.001	27	view →
CHOL	OS	Tertile	All	0.089	0.673	.018	18	view →
UCS	OS	Tertile	II,III,IV	0.638	0.281	.013	18	view →
CESC	OS	Quartile	II,III,IV	0.873	0.632	.015	12	view →
KICH	DFS	Tertile	IV	0.269	0.784	.045	9	view →
PAAD	DFS	Tertile	III,IV	0.152	0.821	.045	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

NEUROG2-AS1–KIRC (DFS)

Open the KIRC breakdown →