NEURL4

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NEURL4 mutation is significantly associated with the total protein of many other genes, with 62 significant associations in total. COAD shows the largest number of these associations.

The most reproducible NEURL4-associated genes across cancer lineages are ATM, eEF2, and Cyclin-E2. Each is linked with NEURL4 in more than 3 cancer types. Because this analysis shows association rather than direction, both NEURL4-to-partner and partner-to-NEURL4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEURL4→partner) and Y-score (partner→NEURL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADATM →-0.633-2.222<.001.00934
COADeEF2 →+0.393+1.874<.001.04933
COADCyclin-E2 →+0.203+3.195.021.00933
COADEGFR_pY1068 →-0.495-2.898<.001.00123
COADeIF4E →+0.255+3.472<.001.00232
COADGAPDH →+0.774+3.459<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

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