NEURL3

Across TCGA patient cohorts, NEURL3 mutation is significantly associated with the RNA expression of many other genes, with 276 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible NEURL3-associated genes across cancer lineages are RN7SL869P, RNU6-217P, and TSPY4. Each is linked with NEURL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEURL3-to-partner and partner-to-NEURL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL869P grouped by NEURL3-low versus NEURL3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEURL3→partner) and Y-score (partner→NEURL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL869P →	+0.061	+4.810	<.001	.002	3	2
LUAD	RNU6-217P →	+0.198	+7.930	<.001	.008	3	1
LUAD	TSPY4 →	+0.069	+7.930	<.001	.008	3	1
SKCM	FTLP15 →	+0.213	+3.329	<.001	.007	3	1
SKCM	AK4P6 →	+0.050	+3.394	<.001	.001	3	1
SKCM	USH2A-AS1 →	+0.066	+2.978	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 276 associations by consensus.

RN7SL869P by NEURL3 expression — SKCM

Explore this box plot interactively →