Across TCGA cell cohorts, NEURL1B mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NEURL1B-associated genes across cancer lineages are NLRP8, SUPT20HL1, and AKAP4. Each is linked with NEURL1B in more than 1 cancer types. Because this analysis shows association rather than direction, both NEURL1B-to-partner and partner-to-NEURL1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEURL1B→partner) and Y-score (partner→NEURL1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	NLRP8 →	+0.006	+5.196	<.001	.005	3	1
OVARY	SUPT20HL1 →	+0.123	+5.807	<.001	.001	3	1
LUNG_NSCLC_LUAD	AKAP4 →	+0.014	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	FBXO40 →	+0.005	+4.189	.004	.002	3	1
LUNG_NSCLC_LUAD	DCSTAMP →	+0.096	+3.734	<.001	.006	3	1
LUNG_NSCLC_LUAD	SIGLECL1 →	+0.022	+4.681	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

NEURL1B survival (RNA) · tumor vs normal (RNA) · all NEURL1B data types