NEU3

Across TCGA cell cohorts, NEU3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,877 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NEU3-associated GO terms across cancer lineages are Negative regulation of clathrin-dependent endocytosis, Microtubule polymerization, and Centrosome cycle. Each is linked with NEU3 in more than 17 cancer types. Because this analysis shows association rather than direction, both NEU3-to-partner and partner-to-NEU3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of clathrin-dependent endocytosis grouped by NEU3-low versus NEU3-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEU3→partner) and Y-score (partner→NEU3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of clathrin-dependent endocytosis →	+0.141	+0.587	.001	<.001	3	18
BONE	Microtubule polymerization →	+0.102	+0.671	<.001	<.001	3	15
BLOOD_Lymphoma	Centrosome cycle →	+0.075	+1.067	<.001	<.001	3	14
PANCREAS	Microtubule organizing center organization →	+0.090	+1.236	<.001	<.001	3	14
SOFT_TISSUE	Regulation of clathrin-dependent endocytosis →	+0.099	+0.830	<.001	<.001	3	14
BLOOD_Lymphoma	Positive regulation of DNA metabolic process →	+0.053	+0.791	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,877 associations by consensus.

Negative regulation of clathrin-dependent endocytosis by NEU3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →