Across TCGA patient cohorts, NEU1 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. COAD shows the largest number of these associations.

The most reproducible NEU1-associated genes across cancer lineages are PCNA, p27_pT157, and Src_pY416. Each is linked with NEU1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NEU1-to-partner and partner-to-NEU1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEU1→partner) and Y-score (partner→NEU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PCNA →	+0.316	+2.820	.020	.035	3	3
COAD	p27_pT157 →	+0.244	+2.815	.002	.036	2	2
COAD	Src_pY416 →	+0.377	+2.815	.012	.036	3	1
COAD	CD49b →	+0.668	+2.815	<.001	.036	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

NEU1 survival (RNA) · tumor vs normal (RNA) · all NEU1 data types