Across TCGA cell cohorts, NEU1 mutation is significantly associated with the RNA expression of many other genes, with 78 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NEU1-associated genes across cancer lineages are ARGFX, SLC5A4, and SLC32A1. Each is linked with NEU1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEU1-to-partner and partner-to-NEU1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEU1→partner) and Y-score (partner→NEU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ARGFX →	+0.008	+3.700	<.001	.009	3	1
BLOOD_Leukemia	SLC5A4 →	+0.270	+3.471	<.001	.004	3	1
BLOOD_Leukemia	SLC32A1 →	+0.756	+3.486	<.001	<.001	3	1
BLOOD_Leukemia	TNFSF8 →	+1.519	+3.672	.001	.003	3	1
BLOOD_Leukemia	PHOX2B →	+0.020	+3.966	<.001	<.001	3	1
BLOOD_Leukemia	ELOVL4 →	+3.198	+3.392	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 78 associations by consensus.

Exploration

NEU1 survival (RNA) · tumor vs normal (RNA) · all NEU1 data types