NETO2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NETO2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,515 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NETO2-associated genes across cancer lineages are NCAN, ENPP4, and TSHZ1. Each is linked with NETO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NETO2-to-partner and partner-to-NETO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NETO2 versus NCAN in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NETO2→partner) and Y-score (partner→NETO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMNCAN →+2.269+0.642<.001.00132
GBMENPP4 →-1.473-0.615<.001.00132
LUADTSHZ1 →+0.806+1.090<.001.00532
GBMH2AC21 →+0.746+0.498<.001.00232
GBMTBKBP1 →+0.570+0.723<.001<.00132
GBMC9orf129 →+0.648+0.541.003.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,515 associations by consensus.

NETO2 vs NCAN — GBM

Per-sample scatter of NETO2 vs NCAN in GBM (Pearson r = 0.36).

Explore this scatter interactively →

Exploration