NETO2

Across TCGA cell cohorts, NETO2 mutation is significantly associated with the RNA expression of many other genes, with 92 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NETO2-associated genes across cancer lineages are PTH, PRSS54, and OR52K2. Each is linked with NETO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NETO2-to-partner and partner-to-NETO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTH grouped by NETO2-low versus NETO2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NETO2→partner) and Y-score (partner→NETO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PTH →	+0.023	+6.247	<.001	<.001	3	2
BLOOD_Lymphoma	PRSS54 →	+0.074	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR52K2 →	+0.012	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	S100A7A →	+0.056	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	IFNL3 →	+0.100	+5.209	.001	.005	3	1
BLOOD_Lymphoma	KRTAP5-11 →	+0.018	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 92 associations by consensus.

PTH by NETO2 expression — BLOOD_Lymphoma

Explore this box plot interactively →