NEPRO

Across TCGA cell cohorts, NEPRO RNA expression is significantly associated with the go_rna of many other GO terms, with 3,082 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NEPRO-associated GO terms across cancer lineages are Protein desumoylation, Positive regulation of organelle assembly, and Protein localization to chromosome. Each is linked with NEPRO in more than 13 cancer types. Because this analysis shows association rather than direction, both NEPRO-to-partner and partner-to-NEPRO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein desumoylation grouped by NEPRO-low versus NEPRO-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEPRO→partner) and Y-score (partner→NEPRO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Protein desumoylation →	+0.117	+0.719	<.001	<.001	3	14
STOMACH	Positive regulation of organelle assembly →	+0.068	+0.662	.005	.006	3	14
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome →	+0.097	+0.661	.001	<.001	3	14
OVARY	Monoubiquitinated protein deubiquitination →	+0.109	+0.734	<.001	<.001	3	14
KIDNEY	Vesicle tethering to Golgi →	+0.115	+0.728	<.001	<.001	3	14
LUNG_SCLC	Protein sumoylation →	+0.069	+0.431	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,082 associations by consensus.

Protein desumoylation by NEPRO expression — URINARY_TRACT

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