NEMP1

Across TCGA patient cohorts, NEMP1 mutation is significantly associated with the RNA expression of many other genes, with 1,204 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEMP1-associated genes across cancer lineages are RN7SKP250, MIR6842, and MIR6857. Each is linked with NEMP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NEMP1-to-partner and partner-to-NEMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP250 grouped by NEMP1-low versus NEMP1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEMP1→partner) and Y-score (partner→NEMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RN7SKP250 →	+0.187	+5.182	<.001	.007	3	3
BLCA	MIR6842 →	+0.510	+5.177	<.001	.007	3	3
UCEC	MIR6857 →	+0.315	+3.095	<.001	<.001	3	2
COAD	RNU6-325P →	+0.359	+7.741	<.001	.009	3	2
COAD	RNU6-1194P →	+0.785	+7.741	<.001	.009	3	2
COAD	MIR4535 →	+0.551	+7.741	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,204 associations by consensus.

RN7SKP250 by NEMP1 expression — HNSC

Explore this box plot interactively →