NEMP1

Across TCGA patient cohorts, NEMP1 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEMP1-associated genes across cancer lineages are JNK2, p70-S6K, and PCNA. Each is linked with NEMP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEMP1-to-partner and partner-to-NEMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by NEMP1-low versus NEMP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEMP1→partner) and Y-score (partner→NEMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.303	+2.459	.001	.020	3	1
UCEC	p70-S6K →	+0.196	+2.189	.034	.034	3	1
UCEC	PCNA →	+0.242	+2.459	.020	.020	3	1
UCEC	PDCD4 →	-0.586	-2.459	.009	.020	3	1
UCEC	Annexin-1 →	+0.615	+3.019	.015	.019	3	1
UCEC	Caspase-7-cleavedD198 →	+0.861	+2.459	.002	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

JNK2 by NEMP1 expression — UCEC

Explore this box plot interactively →