NEMF

Across TCGA patient cohorts, NEMF protein abundance is significantly associated with the RNA expression of many other genes, with 9,324 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible NEMF-associated genes across cancer lineages are L2HGDH, POLE2, and LRR1. Each is linked with NEMF in more than 7 cancer types. Because this analysis shows association rather than direction, both NEMF-to-partner and partner-to-NEMF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEMF versus L2HGDH in HNSC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEMF→partner) and Y-score (partner→NEMF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	L2HGDH →	+0.728	+0.332	<.001	.001	3	8
HNSC	POLE2 →	+0.685	+0.297	.009	.003	3	7
OV	LRR1 →	+0.653	+0.273	<.001	<.001	3	6
HNSC	RPL36AL →	+0.920	+0.225	.009	.006	1	8
LSCC	DNAAF2 →	+0.506	+0.234	<.001	<.001	3	6
HNSC	FKBP3 →	+0.634	+0.217	.001	.004	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,324 associations by consensus.

NEMF vs L2HGDH — HNSC

Explore this scatter interactively →