NEMF

Across TCGA patient cohorts, NEMF mutation is significantly associated with the RNA expression of many other genes, with 5,921 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEMF-associated genes across cancer lineages are SNX24, MSANTD3, and PPP2R5B. Each is linked with NEMF in more than 2 cancer types. Because this analysis shows association rather than direction, both NEMF-to-partner and partner-to-NEMF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNX24 grouped by NEMF-low versus NEMF-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEMF→partner) and Y-score (partner→NEMF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNX24 →	+0.297	+1.637	.009	.001	3	3
UCEC	MSANTD3 →	+0.705	+3.513	<.001	<.001	3	3
UCEC	PPP2R5B →	+0.427	+1.936	<.001	.002	3	3
KIRP	RNU6-1127P →	+0.609	+5.497	<.001	.004	3	3
SKCM	RNU6-1305P →	+0.377	+4.224	<.001	.002	3	3
BRCA	MIR6826 →	+0.520	+3.264	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,921 associations by consensus.

SNX24 by NEMF expression — UCEC

Explore this box plot interactively →