NEMF

Across TCGA cell cohorts, NEMF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,188 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NEMF-associated GO terms across cancer lineages are mRNA 5'-splice site recognition, Vesicle tethering, and Regulation of mRNA splicing, via spliceosome. Each is linked with NEMF in more than 16 cancer types. Because this analysis shows association rather than direction, both NEMF-to-partner and partner-to-NEMF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA 5'-splice site recognition grouped by NEMF-low versus NEMF-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEMF→partner) and Y-score (partner→NEMF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	mRNA 5'-splice site recognition →	+0.135	+0.627	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Vesicle tethering →	+0.113	+0.995	<.001	<.001	3	16
BLOOD_Lymphoma	Regulation of mRNA splicing, via spliceosome →	+0.088	+0.851	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	DNA damage tolerance →	+0.075	+0.742	.006	.005	2	14
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.068	+0.987	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	DNA recombination →	+0.081	+1.023	.002	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,188 associations by consensus.

mRNA 5'-splice site recognition by NEMF expression — LARGE_INTESTINE

Explore this box plot interactively →