NEMF

Across TCGA cell cohorts, NEMF mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NEMF-associated genes across cancer lineages are GAGE12E, ART4, and MBD3L3. Each is linked with NEMF in more than 1 cancer types. Because this analysis shows association rather than direction, both NEMF-to-partner and partner-to-NEMF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE12E grouped by NEMF-low versus NEMF-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEMF→partner) and Y-score (partner→NEMF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	GAGE12E →	+0.090	+4.930	<.001	.008	3	2
BLOOD_Leukemia	ART4 →	+0.696	+3.729	.009	.005	3	2
BLOOD_Leukemia	MBD3L3 →	+0.018	+3.289	.004	.009	3	2
SOFT_TISSUE	H2BC1 →	+0.433	+5.977	<.001	.001	3	1
SOFT_TISSUE	H2AC1 →	+0.193	+5.977	<.001	.001	3	1
SOFT_TISSUE	KRTAP10-1 →	+0.034	+5.369	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

GAGE12E by NEMF expression — SOFT_TISSUE

Explore this box plot interactively →