Across TCGA cell cohorts, NELL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,426 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NELL2-associated GO terms across cancer lineages are Calcium ion homeostasis, DNA-templated transcription initiation, and Epigenetic regulation of gene expression. Each is linked with NELL2 in more than 9 cancer types. Because this analysis shows association rather than direction, both NELL2-to-partner and partner-to-NELL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NELL2→partner) and Y-score (partner→NELL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Calcium ion homeostasis →	-0.110	-4.094	.001	.002	3	10
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.075	+1.956	<.001	<.001	3	10
BONE	Epigenetic regulation of gene expression →	+0.086	+5.160	<.001	<.001	3	10
BONE	Taxis →	-0.109	-5.902	<.001	<.001	3	9
BONE	Chemotaxis →	-0.109	-5.902	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Gamma-aminobutyric acid signaling pathway →	-0.302	-3.367	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,426 associations by consensus.

Exploration

NELL2 survival (RNA) · tumor vs normal (RNA) · all NELL2 data types