Across TCGA cell cohorts, NELL2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,603 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NELL2-associated genes across cancer lineages are CAPZB, CAPZA1, and SCP2. Each is linked with NELL2 in more than 8 cancer types. Because this analysis shows association rather than direction, both NELL2-to-partner and partner-to-NELL2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NELL2→partner) and Y-score (partner→NELL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CAPZB →	+0.677	+0.363	<.001	.004	3	9
BREAST	CAPZA1 →	+0.585	+0.388	.005	.002	3	7
OESOPHAGUS	SCP2 →	+0.910	+0.647	.001	<.001	3	7
KIDNEY	CDC42 →	+0.995	+0.552	.007	.005	2	7
OESOPHAGUS	HSPB11 →	+0.936	+0.507	.002	.005	3	6
SKIN	SAMD9L →	+1.591	+0.414	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,603 associations by consensus.

Exploration

NELL2 survival (RNA) · tumor vs normal (RNA) · all NELL2 data types