Across TCGA cell cohorts, NELL2 mutation is significantly associated with the RNA expression of many other genes, with 514 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NELL2-associated genes across cancer lineages are OR52E8, CCER1, and IQCF6. Each is linked with NELL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NELL2-to-partner and partner-to-NELL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NELL2→partner) and Y-score (partner→NELL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR52E8 →	+0.020	+4.906	<.001	.006	3	2
PANCREAS	CCER1 →	+0.006	+5.614	<.001	.002	3	2
LUNG_NSCLC_LUAD	IQCF6 →	+0.055	+2.777	<.001	.004	3	2
BLOOD_Lymphoma	GAGE10 →	+0.256	+3.459	<.001	.004	3	2
LARGE_INTESTINE	RIC8B →	+0.469	+3.502	.006	.001	3	2
LARGE_INTESTINE	SDHB →	+0.456	+3.588	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 514 associations by consensus.

Exploration

NELL2 survival (RNA) · tumor vs normal (RNA) · all NELL2 data types