Across TCGA cell cohorts, NELFE RNA expression is significantly associated with the go_rna of many other GO terms, with 2,646 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NELFE-associated GO terms across cancer lineages are Protein peptidyl-prolyl isomerization, GDP-mannose biosynthetic process, and Pyrimidine nucleotide biosynthetic process. Each is linked with NELFE in more than 12 cancer types. Because this analysis shows association rather than direction, both NELFE-to-partner and partner-to-NELFE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NELFE→partner) and Y-score (partner→NELFE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein peptidyl-prolyl isomerization →	+0.123	+0.517	<.001	.001	3	13
LARGE_INTESTINE	GDP-mannose biosynthetic process →	+0.131	+0.457	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Pyrimidine nucleotide biosynthetic process →	+0.086	+0.527	.002	.002	3	10
BLOOD_Leukemia	Transcription initiation at RNA polymerase II promoter →	+0.043	+0.450	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Response to heat →	+0.109	+0.894	<.001	<.001	3	8
BREAST	Export across plasma membrane →	-0.094	-0.830	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,646 associations by consensus.

Exploration

NELFE survival (RNA) · tumor vs normal (RNA) · all NELFE data types