NELFCD

Across TCGA pan-cancer cohorts, NELFCD mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NELFCD data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NELFCD mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NELFCD expression acts as an unfavorable survival marker, although some lineages such as COAD and GBM show a favorable association.

COAD, GBM, and PDAC are the cancer types where NELFCD mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.913	.015	54	view →
GBM	OS	Quartile	All	0.674	0.345	.006	7	view →
PDAC	OS	Quartile	All	0.346	0.649	.008	7	view →
CCRCC	OS	Median	All	1.000	0.674	.009	5	view →
HNSC	DFS	Quartile	III,IV	0.918	0.678	.018	4	view →
LUAD	OS	Median	All	0.995	0.892	.027	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NELFCD–COAD (DFS)

Open the COAD breakdown →