NELFCD

Across TCGA patient cohorts, NELFCD mutation is significantly associated with the RNA expression of many other genes, with 2,589 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NELFCD-associated genes across cancer lineages are MIR4510, SPEM2, and RNU1-57P. Each is linked with NELFCD in more than 2 cancer types. Because this analysis shows association rather than direction, both NELFCD-to-partner and partner-to-NELFCD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4510 grouped by NELFCD-low versus NELFCD-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NELFCD→partner) and Y-score (partner→NELFCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR4510 →	+0.403	+6.342	<.001	.001	3	3
UCEC	SPEM2 →	+0.145	+1.497	<.001	.006	3	2
UCEC	RNU1-57P →	+0.105	+3.197	<.001	.003	3	2
CESC	DEFA9P →	+1.792	+5.969	<.001	.002	3	2
LUAD	MIR6722 →	+0.252	+4.303	.001	.009	3	2
BRCA	S100A11P7 →	+0.255	+4.382	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,589 associations by consensus.

MIR4510 by NELFCD expression — CESC

Explore this box plot interactively →