NELFCD

Across TCGA cell cohorts, NELFCD RNA expression is significantly associated with the go_rna of many other GO terms, with 5,130 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NELFCD-associated GO terms across cancer lineages are Regulation of double-strand break repair via homologous recombination, Regulation of double-strand break repair, and Negative regulation of t-circle formation. Each is linked with NELFCD in more than 14 cancer types. Because this analysis shows association rather than direction, both NELFCD-to-partner and partner-to-NELFCD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via homologous recombination grouped by NELFCD-low versus NELFCD-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NELFCD→partner) and Y-score (partner→NELFCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of double-strand break repair via homologous recombination →	+0.120	+1.296	<.001	<.001	3	15
SOFT_TISSUE	Regulation of double-strand break repair →	+0.095	+1.125	<.001	<.001	3	15
URINARY_TRACT	Negative regulation of t-circle formation →	+0.126	+0.705	.004	<.001	2	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA metabolic process →	+0.079	+1.478	<.001	<.001	3	14
SOFT_TISSUE	Regulation of DNA repair →	+0.083	+1.134	<.001	<.001	3	14
BONE	Regulation of DNA recombination →	+0.112	+1.237	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,130 associations by consensus.

Regulation of double-strand break repair via homologous recombination by NELFCD expression — SOFT_TISSUE

Explore this box plot interactively →