NELFCD

Across TCGA cell cohorts, NELFCD mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible NELFCD-associated genes across cancer lineages are GP2, CST9, and C12orf40. Each is linked with NELFCD in more than 1 cancer types. Because this analysis shows association rather than direction, both NELFCD-to-partner and partner-to-NELFCD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GP2 grouped by NELFCD-low versus NELFCD-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NELFCD→partner) and Y-score (partner→NELFCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	GP2 →	+0.162	+4.228	<.001	.006	3	1
OVARY	CST9 →	+0.005	+4.807	<.001	.003	3	1
OVARY	C12orf40 →	+0.011	+4.029	<.001	.009	3	1
OVARY	FAM24A →	+0.037	+4.807	<.001	.003	3	1
LARGE_INTESTINE	MAGEB4 →	+0.014	+4.000	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

GP2 by NELFCD expression — OVARY

Explore this box plot interactively →