NELFCD

Across TCGA cell cohorts, NELFCD mutation is significantly associated with the mutation status of many other genes, with 2,969 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NELFCD-associated genes across cancer lineages are MYH10, REM1, and IGFALS. Each is linked with NELFCD in more than 3 cancer types. Because this analysis shows association rather than direction, both NELFCD-to-partner and partner-to-NELFCD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH10 grouped by NELFCD-low versus NELFCD-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NELFCD→partner) and Y-score (partner→NELFCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MYH10 →	+2.340	+4.278	<.001	<.001	1	4
BREAST	REM1 →	+5.297	+5.297	.004	.004	1	3
LARGE_INTESTINE	IGFALS →	+3.215	+3.415	.002	.002	1	3
LARGE_INTESTINE	CABIN1 →	+2.099	+4.064	.001	.001	1	3
STOMACH	TTC39B →	+4.807	+4.807	.008	.008	1	3
OVARY	MMS19 →	+4.977	+4.415	.007	.007	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,969 associations by consensus.

MYH10 by NELFCD expression — LARGE_INTESTINE

Explore this box plot interactively →