Across TCGA patient cohorts, NELFB protein abundance is significantly associated with the RNA expression of many other genes, with 17,416 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NELFB-associated genes across cancer lineages are POLR1C, RFC5, and ZBTB12. Each is linked with NELFB in more than 8 cancer types. Because this analysis shows association rather than direction, both NELFB-to-partner and partner-to-NELFB results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NELFB→partner) and Y-score (partner→NELFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	POLR1C →	+0.581	+0.258	<.001	<.001	3	9
LSCC	RFC5 →	+0.834	+0.284	<.001	<.001	3	8
BRCA	ZBTB12 →	+0.631	+0.218	.001	.002	3	8
LSCC	KLHL23 →	+1.061	+0.255	<.001	<.001	3	8
LSCC	WDR5 →	+0.572	+0.255	<.001	<.001	3	7
LSCC	NELFE →	+0.490	+0.229	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,416 associations by consensus.

Exploration

NELFB survival (RNA) · tumor vs normal (RNA) · all NELFB data types