Across TCGA patient cohorts, NELFB mutation is significantly associated with the RNA expression of many other genes, with 573 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NELFB-associated genes across cancer lineages are RN7SL553P, TRAJ47, and MFN1P1. Each is linked with NELFB in more than 2 cancer types. Because this analysis shows association rather than direction, both NELFB-to-partner and partner-to-NELFB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NELFB→partner) and Y-score (partner→NELFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL553P →	+0.435	+5.392	<.001	.002	3	3
UCEC	TRAJ47 →	+0.556	+2.198	<.001	.001	3	2
BLCA	MFN1P1 →	+0.041	+4.913	<.001	<.001	3	2
HNSC	MIR3915 →	+0.388	+7.954	<.001	.008	3	2
BLCA	MIR325 →	+0.504	+5.455	<.001	.001	3	2
UCEC	PPIAP17 →	+0.089	+1.971	.007	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 573 associations by consensus.

Exploration

NELFB survival (RNA) · tumor vs normal (RNA) · all NELFB data types