Across TCGA patient cohorts, NELFB mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NELFB-associated genes across cancer lineages are Caspase-7-cleavedD198, eEF2, and ERK2. Each is linked with NELFB in more than 2 cancer types. Because this analysis shows association rather than direction, both NELFB-to-partner and partner-to-NELFB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NELFB→partner) and Y-score (partner→NELFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.724	+2.000	.001	.029	3	3
UCEC	eEF2 →	+0.336	+2.000	.016	.010	3	2
UCEC	ERK2 →	+0.212	+2.000	.004	.010	3	2
UCEC	FOXO3a_pS318_S321 →	-0.110	-2.459	.025	.018	3	2
UCEC	mTOR_pS2448 →	-0.167	-3.308	.004	.009	3	2
UCEC	GAPDH →	+0.430	+3.169	.041	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

NELFB survival (RNA) · tumor vs normal (RNA) · all NELFB data types