Across TCGA cell cohorts, NELFB mutation is significantly associated with the RNA expression of many other genes, with 132 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NELFB-associated genes across cancer lineages are TEX13A, TBX5, and FTMT. Each is linked with NELFB in more than 1 cancer types. Because this analysis shows association rather than direction, both NELFB-to-partner and partner-to-NELFB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NELFB→partner) and Y-score (partner→NELFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TEX13A →	+0.027	+4.643	<.001	.005	3	2
BLOOD_Lymphoma	TBX5 →	+0.729	+4.350	<.001	.005	3	2
SOFT_TISSUE	FTMT →	+0.086	+5.977	<.001	.001	3	1
STOMACH	SPANXN4 →	+0.075	+4.285	<.001	.007	3	1
STOMACH	MPC1L →	+0.185	+4.794	<.001	.001	3	1
BREAST	VSIG4 →	+0.352	+4.421	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 132 associations by consensus.

Exploration

NELFB survival (RNA) · tumor vs normal (RNA) · all NELFB data types