NEK9

Across TCGA patient cohorts, NEK9 protein abundance is significantly associated with the RNA expression of many other genes, with 15,757 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NEK9-associated genes across cancer lineages are ALKBH1, FCF1, and EIF2B2. Each is linked with NEK9 in more than 6 cancer types. Because this analysis shows association rather than direction, both NEK9-to-partner and partner-to-NEK9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEK9 versus ALKBH1 in BRCA, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK9→partner) and Y-score (partner→NEK9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ALKBH1 →	+0.654	+0.335	<.001	<.001	3	7
HNSC	FCF1 →	+0.535	+0.215	<.001	<.001	3	7
OV	EIF2B2 →	+0.493	+0.286	<.001	<.001	3	7
OV	ISCA2 →	+0.640	+0.244	.001	.005	3	7
OV	AP4S1 →	+0.607	+0.188	<.001	.004	3	6
HNSC	VTI1B →	+0.381	+0.238	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,757 associations by consensus.

NEK9 vs ALKBH1 — BRCA

Explore this scatter interactively →