NEK7

Across TCGA patient cohorts, NEK7 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,361 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NEK7-associated proteins across cancer lineages are OTUD7B, PPIF, and CAMSAP2. Each is linked with NEK7 in more than 4 cancer types. Because this analysis shows association rather than direction, both NEK7-to-partner and partner-to-NEK7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEK7 versus OTUD7B in COAD, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK7→partner) and Y-score (partner→NEK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OTUD7B →	+0.245	+0.563	<.001	.003	3	5
PDAC	PPIF →	-0.417	-0.524	<.001	<.001	3	5
UCEC	CAMSAP2 →	+0.273	+0.356	<.001	<.001	3	5
PDAC	MRPL58 →	-0.312	-0.336	<.001	.007	3	5
CCRCC	LMNA →	+0.350	+0.257	<.001	.003	3	5
CCRCC	PPP1R12A →	+0.232	+0.339	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,361 associations by consensus.

NEK7 vs OTUD7B — COAD

Explore this scatter interactively →