NEK7

Across TCGA patient cohorts, NEK7 protein abundance is significantly associated with the RNA expression of many other genes, with 16,073 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NEK7-associated genes across cancer lineages are DDR2, TAGLN, and MSRB3. Each is linked with NEK7 in more than 8 cancer types. Because this analysis shows association rather than direction, both NEK7-to-partner and partner-to-NEK7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEK7 versus DDR2 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK7→partner) and Y-score (partner→NEK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DDR2 →	+1.608	+0.271	<.001	<.001	3	9
OV	TAGLN →	+1.357	+0.239	<.001	.001	3	8
OV	MSRB3 →	+1.348	+0.317	<.001	<.001	3	8
OV	MYLK →	+1.398	+0.317	<.001	<.001	3	7
OV	RBMS3 →	+0.777	+0.316	<.001	<.001	3	7
UCEC	NEXN →	+1.095	+0.342	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,073 associations by consensus.

NEK7 vs DDR2 — OV

Explore this scatter interactively →