NEK7

Across TCGA cell cohorts, NEK7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,175 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NEK7-associated GO terms across cancer lineages are Cellular response to environmental stimulus, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Cellular response to abiotic stimulus. Each is linked with NEK7 in more than 10 cancer types. Because this analysis shows association rather than direction, both NEK7-to-partner and partner-to-NEK7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to environmental stimulus grouped by NEK7-low versus NEK7-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK7→partner) and Y-score (partner→NEK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cellular response to environmental stimulus →	+0.045	+1.213	<.001	<.001	3	11
LIVER	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.060	+0.955	.007	.007	3	11
SKIN	Cellular response to abiotic stimulus →	+0.045	+1.213	<.001	<.001	3	11
OVARY	Regulation of protein modification by small protein conjugation or removal →	+0.062	+0.779	<.001	<.001	3	11
BONE	Response to hydrostatic pressure →	+0.188	+1.319	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of macrophage fusion →	+0.196	+0.778	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,175 associations by consensus.

Cellular response to environmental stimulus by NEK7 expression — SKIN

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