NEK6

Across TCGA patient cohorts, NEK6 protein abundance is significantly associated with the RNA expression of many other genes, with 15,394 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NEK6-associated genes across cancer lineages are MS4A6A, PLXNC1, and ANTXR2. Each is linked with NEK6 in more than 5 cancer types. Because this analysis shows association rather than direction, both NEK6-to-partner and partner-to-NEK6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEK6 versus MS4A6A in OV, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK6→partner) and Y-score (partner→NEK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MS4A6A →	+1.022	+0.372	.001	.007	3	6
OV	PLXNC1 →	+0.969	+0.512	<.001	<.001	3	5
OV	ANTXR2 →	+0.758	+0.450	<.001	<.001	3	5
BRCA	TGFBR2 →	+0.966	+0.351	<.001	<.001	3	5
HNSC	LAIR1 →	+1.064	+0.341	<.001	<.001	3	5
OV	DPYD →	+1.019	+0.387	<.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,394 associations by consensus.

NEK6 vs MS4A6A — OV

Explore this scatter interactively →