NEK6

Across TCGA patient cohorts, NEK6 mutation is significantly associated with the RNA expression of many other genes, with 1,643 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEK6-associated genes across cancer lineages are LINC02854, RN7SL649P, and MIR4418. Each is linked with NEK6 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEK6-to-partner and partner-to-NEK6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02854 grouped by NEK6-low versus NEK6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK6→partner) and Y-score (partner→NEK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02854 →	+0.037	+2.919	<.001	.007	3	2
UCEC	RN7SL649P →	+0.139	+2.124	<.001	.009	3	2
COAD	MIR4418 →	+0.893	+4.893	<.001	.005	3	2
BRCA	ZYXP1 →	+0.164	+7.471	<.001	.008	3	1
BRCA	MIR3648-1 →	+0.356	+8.057	<.001	.005	3	1
CESC	TRAV11 →	+0.186	+4.934	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,643 associations by consensus.

LINC02854 by NEK6 expression — UCEC

Explore this box plot interactively →