Across TCGA patient cohorts, NEK5 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,512 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NEK5-associated proteins across cancer lineages are WDR35, IFT122, and WDR19. Each is linked with NEK5 in more than 6 cancer types. Because this analysis shows association rather than direction, both NEK5-to-partner and partner-to-NEK5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK5→partner) and Y-score (partner→NEK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDR35 →	+0.361	+0.708	<.001	<.001	3	7
LSCC	IFT122 →	+0.420	+0.675	<.001	<.001	3	7
BRCA	WDR19 →	+0.437	+1.065	<.001	<.001	3	6
BRCA	DDAH1 →	+0.690	+0.897	<.001	<.001	3	6
UCEC	DYNC2H1 →	+0.487	+0.719	<.001	<.001	3	6
GBM	IFT74 →	+0.420	+0.750	.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,512 associations by consensus.

Exploration

NEK5 survival (RNA) · tumor vs normal (RNA) · all NEK5 data types