NEK4P2

Across TCGA pan-cancer cohorts, NEK4P2 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated NEK4P2 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NEK4P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NEK4P2 expression acts as an unfavorable survival marker.

COAD, BLCA, and KIRC are the cancer types where NEK4P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	III,IV	0.360	0.798	<.001	111	view →
BLCA	OS	Tertile	All	0.124	0.693	<.001	78	view →
KIRC	OS	Tertile	All	0.424	0.648	.005	60	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	54	view →
UVM	OS	Tertile	All	0.266	0.792	<.001	45	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
LAML	DFS	Tertile	All	0.293	0.635	<.001	36	view →
UCS	DFS	Tertile	IV	0.230	0.767	.009	36	view →
THCA	OS	Tertile	All	0.951	0.992	<.001	36	view →
UCEC	OS	Tertile	All	0.833	0.933	.010	36	view →
LUSC	DFS	Tertile	II,III,IV	0.485	0.732	.003	18	view →
GBM	OS	Median	All	0.288	0.489	.007	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

NEK4P2–COAD (OS)

Open the COAD breakdown →