NEK2P2

Across TCGA pan-cancer cohorts, NEK2P2 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated NEK2P2 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NEK2P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NEK2P2 expression acts as an unfavorable survival marker.

LUAD, UCEC, and KIRP are the cancer types where NEK2P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.381	0.704	.003	48	view →
UCEC	DFS	Tertile	All	0.527	0.672	.014	36	view →
KIRP	DFS	Tertile	All	0.601	0.926	<.001	21	view →
BRCA	OS	Tertile	II,III,IV	0.839	0.917	.022	18	view →
CESC	OS	Tertile	III,IV	0.167	0.657	.044	18	view →
SARC	DFS	Tertile	All	0.061	0.596	<.001	15	view →
LIHC	DFS	Tertile	II,III,IV	0.115	0.469	.016	15	view →
MESO	DFS	Tertile	III,IV	0.277	0.441	.042	9	view →
PCPG	DFS	Tertile	All	0.229	0.821	.031	9	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

NEK2P2–LUAD (OS)

Open the LUAD breakdown →