NEK2P1

Across TCGA patient cohorts, NEK2P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,634 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NEK2P1-associated GO terms across cancer lineages are Positive regulation of chromosome organization, Sister chromatid segregation, and Telomere maintenance. Each is linked with NEK2P1 in more than 12 cancer types. Because this analysis shows association rather than direction, both NEK2P1-to-partner and partner-to-NEK2P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome organization grouped by NEK2P1-low versus NEK2P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK2P1→partner) and Y-score (partner→NEK2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of chromosome organization →	+0.088	+0.054	<.001	<.001	3	13
STAD	Sister chromatid segregation →	+0.100	+0.062	<.001	<.001	3	13
STAD	Telomere maintenance →	+0.084	+0.057	<.001	<.001	3	13
STAD	Macromolecule methylation →	+0.079	+0.058	<.001	<.001	3	13
STAD	Positive regulation of DNA metabolic process →	+0.083	+0.063	<.001	<.001	3	12
STAD	Mitotic nuclear division →	+0.096	+0.055	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,634 associations by consensus.

Positive regulation of chromosome organization by NEK2P1 expression — STAD

Explore this box plot interactively →