NEK11

Across TCGA patient cohorts, NEK11 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,737 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NEK11-associated proteins across cancer lineages are IFT22, IFT46, and NIT2. Each is linked with NEK11 in more than 5 cancer types. Because this analysis shows association rather than direction, both NEK11-to-partner and partner-to-NEK11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEK11 versus IFT22 in BRCA, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK11→partner) and Y-score (partner→NEK11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IFT22 →	+0.336	+0.997	<.001	<.001	3	6
OV	IFT46 →	+0.644	+0.775	<.001	<.001	3	6
PDAC	NIT2 →	+0.311	+0.368	<.001	<.001	3	6
UCEC	TTC25_S542 →	+1.306	+0.927	<.001	.004	3	6
OV	DLG1 →	+0.405	+0.686	<.001	<.001	3	5
OV	FBXW9 →	+0.552	+0.815	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,737 associations by consensus.

NEK11 vs IFT22 — BRCA

Explore this scatter interactively →