NEK11

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NEK11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,325 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NEK11-associated GO terms across cancer lineages are Macroautophagy, Endosomal transport, and Vacuolar transport. Each is linked with NEK11 in more than 13 cancer types. Because this analysis shows association rather than direction, both NEK11-to-partner and partner-to-NEK11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by NEK11-low versus NEK11-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK11→partner) and Y-score (partner→NEK11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHMacroautophagy →+0.062+1.026.004.002214
STOMACHEndosomal transport →+0.060+1.486.001<.001313
OVARYVacuolar transport →+0.049+0.980<.001<.001312
STOMACHProcess utilizing autophagic mechanism →+0.062+0.959.005.004212
STOMACHAutophagy →+0.062+0.959.005.004212
STOMACHVacuole organization →+0.059+1.347.003<.001311
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,325 associations by consensus.

Macroautophagy by NEK11 expression — STOMACH

Box plot of Macroautophagy in NEK11-low vs NEK11-high samples in STOMACH.

Explore this box plot interactively →

Exploration